Dr. McBride received his Ph.D. from the University of California Riverside under the mentorship of Dr. Victor G. J. Rodgers where his research focused on understanding the phenomena of crowded protein osmotic pressure and its applications to medical devices. During his Ph.D., he received a number of Fellowships, including an NSF IGERT Fellowship in Video Bioinformatics and a DOE GAANN Fellowship. His postdoctoral training occurred under the tutelage of Dr. John H. Zhang at Loma Linda University where he studied translational neuroscience research with an emphasis on cerebrovascular disease. During his postdoctoral work, Dr. McBride received an NIH F32 award from NHLBI to develop and study an animal model of vasovagal syncope. He has authored numerous papers in the fields of engineering and neuroscience. In 2017, Dr. McBride joined the Vivian L. Smith Department of Neurosurgery as an Assistant Professor.

The research in Dr. McBride’s lab is focused on understanding the pathophysiology of subarachnoid hemorrhage (SAH), particularly focusing on delayed cerebral ischemia (DCI). Delayed cerebral ischemia after SAH is a critical factor in the poor prognosis of surviving patients, and currently we still do not fully understand the mechanisms causing DCI. The McBride lab is using live imaging to understand the cerebrovascular dynamics as they are related to ensuing injury subsequent to SAH. Additionally, we are identifying novel therapeutic targets and developing strategies aimed at attenuating DCI following SAH. The McBride lab is funded by an NIH R01 and grants from the Brain Aneurysm Foundation.

Dr. McBride is collaborating with Dr. Spiros Blackburn to identify biomarkers of DCI post-SAH. The goal of this work is to investigate markers of coagulation and inflammation to determine which patients are at high risk for developing DCI and poor outcome after SAH. This work will also elucidate novel therapeutic targets for preventing DCI

Education & Training

PhD

Doctorate of Philosophy in Bioengineering, University of California, Riverside, CA