Large and rare duplications and deletions in a chromosome region known as 22q11.2, which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, according to a new study led by UTHealth Houston researchers.
Male adolescents and young adults with cancer have a slightly elevated risk of having preterm birth and children with low birth weight, but no increased risk of birth defects in their offspring, according to research by UTHealth Houston. The population-based study was recently published in the Journal of the National Cancer Institute.
In an effort to close the gap in neurological outcomes for underserved populations, a UTHealth Houston project funded with $2.9 million from the National Institutes of Health (NIH) will engage community partners to improve the design of clinical trials.