Research Coordinator for the I-ACQUIRE study under the Director of the Pediatric Stroke Program at the Institute for Stroke and Cerebrovascular Diseases at UTHealth Houston, Stuart Fraser, MD.

Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-AQUIRE)

The UTHealth Pediatric Stroke Program is part of a nation-wide research study named I-ACQUIRE. This study is focused on helping young children who had a stroke when they were born. Specifically, we are trying to help children who had what is called a Perinatal Arterial Ischemic Stroke (PAS). Children who have difficulty moving one side of the body or the other from this type of stroke are potentially candidates.

In this study, we're testing two different levels of a new kind of therapy (I-ACQUIRE) to see how it helps kids aged 8 to 36 months who had PAS. This study will include 240 children, randomly divided into three groups:

1. Moderate Dose group: Children in this group will receive the I-ACQUIRE therapy for 3 hours a day, 5 days a week, for 4 weeks.
2. High Dose group: Children in this group will receive the I-ACQUIRE therapy for 6 hours a day, 5 days a week, for 4 weeks.
3. Usual and Customary group: Children in this group will continue to receive their regular therapy in their community.

We will carefully track each child's progress from the beginning of the therapy, at the end of 4 weeks, and then 6 months after the therapy. Our goal is to learn more about the best ways to help children who have had a PAS.

To see study flyer CLICK HERE

The study is recruiting patients currently. If you are interested in having your child participate in this study or just want more information, feel free to reach out to Samantha Acosta at the email below.

PI: Stuart Fraser, MD

Coordinator: Maria Poblete

Contact: maria.poblete@uth.tmc.edu